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2025

1. Xinyue Wang, Hui Xu, Qing Wang, Jialong Ma, Miao-Chun Lin, Li Zhou, Mengyao Wu, Guoxiu Hao, Yuexin Du, Ao Li, Yuanyuan An, Xiehaoran Zhang, Wei-Ting Chang, I-Chin Chen, Haofan Lu, Jian Li, Hui-Hsu Gavin Tsai*, Haiming Liu*, Fa-Kuen Shieh*, Lien-Yang Chou*. "A Solid-State Crystallization Strategy for Direct Enzyme Encapsulation in Zr-MOFs: Eliminating Harsh pH and Thermal Requirements of Liquid-Phase Synthesis"  Angew. Chem. Int. Ed. (2025) [IF=16.9]

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2024

1. Trung Hieu Vo, Shang-Wei Lin, Miao-Chun Lin, Pu-Yun Kuan, Jing-Hui Chen, Hsin-Kai Huang, Wen-Tzu Liu, Hui Xu, Ao Li, Yu-An Hsu, Lei Wan, Phuc Khanh Lam,* Lien-Yang Chou,* Hsiao-Ching Yang,* and Fa-Kuen Shieh*. "Exploring Enzyme Encapsulation Efficiency in MOFs Using Ecofriendly Approaches" ChemSusChem (2024) [IF=7.5]

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2. Shang-Wei Lin, Phuc Khanh Lam, Chin-Teng Wu, Kuan-Hsuan Su, Chi-Fang Sung, Sen-Ruo Huang, Je-Wei Chang, Orion Shih, Yi-Qi Yeh, Trung Hieu Vo, Heng-Kwong Tsao, Haw-Ting Hsieh, U-Ser Jeng,* Fa-Kuen Shieh,* and Hsiao-Ching Yang*. "Decoding the Biomimetic Mineralization of Metal–Organic Frameworks in Water" ACS Nano (2024) [IF=15.8]

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3. Trung Hieu Vo, Phuc Khanh Lam, Ruei-min Chuang, Fa-Kuen Shieh*, Yu-Jane Sheng*, Heng-Kwong Tsao*. "One-step, additive-free fabrication of highly stretchable and ultra-tough physical polyvinyl alcohol-based eutectogels for strain sensors" Chemical Engineering Journal (2024) [IF=15.1]

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4. Linards Lapčinskis, Andris Šutka*, Martynas Kinka*,  Fa-Kuen Shieh*, Līva Ģērmane, Sergejus Balčiūnas, Artis Linartsa and Robertas Grigalaitisb. "Controlling the magnitude and polarity of surface charges in PEBA polymers by adding UIO-66 MOFs" Materials Advances (2024) [IF=5.0]

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2023

1. Phuc Khanh Lam, Trung Hieu Vo, Jing-Hui Chen, Shang-Wei Lin, Chiao-Ling Kuo, Jian-Jie Liao, Kuan-Yu Chen, Sen-Ruo Huang, Dong Li, Yun-Hsiang Chang, Hsuan-Yi Chen, Haw-Ting Hsieh, Yu-An Hsu, Heng-Kwong Tsao, Hsiao-Ching Yang* and Fa-Kuen Shieh*. "Green and Ultrafast One-Pot Mechanochemical Approach for Efficient Biocatalyst Encapsulation in MOFs: Insights from Experiment and Computation" Journal of Materials Chemistry A (2023) [IF=14.511]

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2. Phuc Khanh Lam, Jian-Jie Liao, Miao-Chun Lin, Yu-Hsiu Li, Tsu-Hao Wang, Hsin-Kai Huang, Yu-An Hsu, Hao-Ying Patterson Hsieh, Pu-Yun Kuan, Ching-Tien Chen, Guo-Xiu Hao, Chia-Kuang Tsung, Kevin C.-W. Wu, Andris Šutka, Martynas Kinka, Lien-Yang Chou*, and Fa-Kuen Shieh*. "Controlled Encapsulation of Gold Nanoparticles into Zr-Metal–Organic Frameworks with Improved Detection Limitation of Volatile Organic Compounds via Surface-Enhanced Raman Scattering" Inorganic Chemistry (2023) [IF=5.436]

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2021

1. H. Lia, A. Kanga, B. Ana, L.-Y. Choua, F.-K. Shiehb, C.-K. Tsungc**, C. Zhong*. "Encapsulation of bacterial cells in cytoprotective ZIF-90 crystals as living composites" Materials Today Bio (2021) [IF=7.348]

Encapsulation of bacterial cells in cytoprotective ZIF-90 crystals as living composites.jp
Creating an Aligned Interface between Nanoparticles and MOFs by Concurrent Replacement of

2. Yang Li, Wei-Shang Lo*, Furui Zhang*, Xiaomeng Si, Lien-Yang Chou, Xiao-Yuan Liu, Benjamin P. Williams, Yu-Hsiu Li, Seung-Hea Jung, Yu-Shen Hsu, Fu-Siang Liao, Fa-Kuen Shieh, Mariam N. Ismail, Wenyu Huang*, and Chia-Kuang Tsung*. "Creating an Aligned Interface between Nanoparticles and MOFs by Concurrent Replacement of Capping Agents" Journal of the American Chemical Society (2021)  [IF=15.419]

3. Pei-Hsiang Hsu, Chien-Chun Chang, Tsu-Hao Wang, Phuc Khanh Lam, Ming-Yu Wei, Ching-Tien Chen, Chin-Yu Chen, Lien-Yang Chou*, and Fa-Kuen Shieh*. "Rapid Fabrication of Biocomposites by Encapsulating Enzymes into Zn-MOF-74 via a Mild Water-Based Approach" ACS Applied Materials & Interfaces (2021)  [IF=9.229] 

Rapid Fabrication of Biocomposites by Encapsulating Enzymes into Zn-MOF-74 via a Mild Wate

2020

1. Sheng-Yu Chen, Wei-Shang Lo, Yi-Da Huang, Xiaomeng Si, Fu-Siang Liao, Shang-Wei Lin, Benjamin P. Williams, Ting-Qian Sun, Hao-Wei Lin, Yuanyuan An, Tu Sun, Yanhang Ma, Hsiao-Ching Yang*, Lien-Yang Chou*, Fa-Kuen Shieh*, Chia-Kuang Tsung*. "Probing Interactions between Metal-Organic Frameworks and Freestanding Enzymes in a Hollow Structure" Nano Letters (2020) [IF=12.344]

2. Hannelore Konnerth, Babasaheb M. Matsagar, Season S. Chen, Martin H.G. Prechtl, Fa-Kuen Shieh*, Kevin C.-W. Wu*. " Metal-organic framework (MOF)-derived catalysts for fine chemical production" Coordination Chemistry Reviews (2020) 213319 [IF=13.476]

Before 2019

  1. Tz-Han Wei, Shi-Hong Wu, Yi-Da Huang, Wei-Shang Lo, Benjamin P. Williams, Sheng-Yu Chen, Hsun-Chih Yang, Yu-Shen Hsu, Zih-Yin Lin, Xin-Hua Chen, Pei-En Kuo, Lien-Yang Chou*, Chia-Kuang Tsung* & Fa-Kuen Shieh*. "Rapid mechanochemical encapsulation of biocatalysts into robust metal–organic frameworks" Nature Communications (2019) 5002 [IF=12.121]
     

  2. Chih-Chiang Chiu, Fa-Kuen Shieh, and Hui-Hsu Gavin Tsai*. "Ligand Exchange in the Synthesis of Metal–Organic Frameworks Occurs Through Acid-Catalyzed Associative Substitution" Inorganic chemistry (2019) [IF=4.84]
     

  3. Saikat Dutta, Jeonghun Kim, Pin-Hsun Hsieh, Yu-Shen Hsu, Yusuf Valentino Kaneti, Fa-Kuen Shieh*, Yusuke Yamauchi*, Kevin C.-W. Wu*. "Nanoarchitectonics of Biofunctionalized Metal–Organic Frameworks with Biological Macromolecules and Living Cells" Small Methods (2019) 1900213 [IF=12.13]
     

  4. Sergejus Balciunas, Mantas Šimėnas*, Diana Pavlovaite, Martynas Kinka, Fa-Kuen Shieh, Kevin C.-W. Wu, Juras Banys, and Robertas Grigalaitis. "Low-Frequency Dipolar Dynamics and Atmospheric Effects in ZIF-90 Metal-Organic Framework" The Journal of Physical Chemistry C (2018) [IF=4.309]
     

  5. Jih Ru Hwu,* D. Balaji Chandrasekhar, Kuo Chu Hwang, Chun-Cheng Lin, Jia-Cherng Horng and Fa-Kuen Shieh. "Reductive Deamination by Benzyne for Deoxy Sugar Synthesis Through a Domino Reaction" ChemistryOpen (2017) 331-335 [IF=2.801]
     

  6. Yusuf Valentino Kaneti, Saikat Dutta, Md. S. A. Hossain, Muhammad J. A. Shiddiky, Kuo-Lun Tung, Fa-Kuen Shieh, Chia-Kuang Tsung, Kevin C.-W. Wu,* and Yusuke Yamauchi*. "Strategies for Improving the Functionality of Zeolitic Imidazolate Frameworks: Tailoring Nanoarchitectures for Functional Applications" Advanced Materials (2017) 1700213 [IF=21.95]
     

  7. Fu-Siang Liao, Wei-Shang Lo, Yu-Shen Hsu, Chang-Cheng Wu, Shao-Chun Wang, Fa-Kuen Shieh,* Joseph V. Morabito, Lien-Yang Chou, Kevin C.-W. Wu, and Chia-Kuang Tsung*. "Shielding Against Unfolding by Embedding Enzymes in Metal-Organic Frameworks via a de novo Approach" Journal of the American Chemical Society (2017) 6530-6533 [IF=14.357]
     

  8. Yi-Hao Huang, Wei-Shang Lo, Yun-Wei Kuo, Wen-Jin Chen, Chia-Her Lin and Fa-Kuen Shieh*. "Green and Rapid Synthesis of Zirconium Metal-organic Frameworks via Mechanochemistry: UiO-66 Analog nanocrystals obtained in one hundred seconds" Chemical Communications (2017) 5818-5821 [IF=6.29]
     

  9. Le Thi Ngoc Chuc, Cheng-Sheng Chen, Wei-Shang Lo, Po-Chuan Shen, Yi-Chen Hsuan, Hui-Hsu Gavin Tsai, Fa-Kuen Shieh*, and Duen-Ren Hou*. "Long-Range Olefin Isomerization Catalyzed by Palladium(0) Nanoparticles" ACS OMEGA (2017) 698-711 [IF=2.58]
     

  10. Chia-I Yen, Szu-Mam Liu, Wei-Shang Lo, Jhe-Wei Wu, Yi-Hsin Liu, Rong-Jie Chein, Renqiang Yang, Kevin C.-W. Wu, Jih Ru Hwu, Nianhan Ma* and Fa-Kuen Shieh*. "Cytotoxicity of Postmodified Zeolitic-Imidazolate Framework-90 (ZIF-90) Nanocrystals: Correlation between Functionality and Toxicity" Chemistry A European Journal (2016) 2925-2929 [IF=5.317]
     

  11. Shao-Chun Wang, Yu-Shen Hsu, Chia-Teng Hsiao, Chang-Cheng Wu, Yu-Chein Sue, Saad M. Alshehri, Tansir Ahamad, Yusuke Yamauchi, Jeffrey E. Chen, Kevin C.-W. Wu*, Fa-Kuen Shieh*. "Annulated Mesoporous Silica as Potent Lanthanide Ion Adsorbents and Magnetic Resonance Contrast Enhancing Agents" Journal of Inorganic and Organometallic Polymers and Materials (2016) 165-171 [IF=1.577]
     

  12. Lien-Yang Chou, Pan Hu, Jia Zhuang, Joseph V. Morabito, Ka Chon Ng, Ya-Chuan Kao, Shao-Chun Wang, Fa-Kuen Shieh, Chun-Hong Kuo* and Chia-Kuang Tsung*. "Formation of Hollow and Mesoporous Structure in Single-Crystalline Microcrystals of Metal-Organic Frameworks via a Double-Solvent Mediated Overgrowth" Nanoscale (2015) 19408-19412 [IF=7.760]
     

  13. Victor Malgras, Qingmin Ji, Yuichiro Kamachi, Taizo Mori, Fa-Kuen Shieh, Kevin C. W. Wu, Katsuhiko Ariga,* and Yusuke Yamauchi*. "Templated Synthesis for Nanoarchitectured Porous Materials" Bulletin of the Chemical Society of Japan (2015) 1171-1200 [IF=1.372]
     

  14. Fa-Kuen Shieh,* Shao-Chun Wang, Chia-I Yen, Chang-Cheng Wu, Saikat Dutta, Lien-Yang Chou, Joseph V. Morabito, Pan Hu, Ming-Hua Hsu, Kevin C.-W. Wu* and Chia-Kuang Tsung*. "Imparting Functionality to Biocatalysts via Embedding Enzymes into Nanoporous Materials by a de novo Approach: Size-Selective Sheltering of Catalase in Metal-Organic Framework Microcrystals" Journal of the American Chemical Society (2015) 4276-4279 [IF=13.038]
     

  15. Malay Pramanik, Fa-Kuen Shieh, Saad M. Alshehri, Zeid Abdullah Alothman, Kevin C.-W. Wu* and Yusuke Yamauchi*. "Template-free synthesis of nanoporous gadolinium phosphonate as a magnetic resonance imaging (MRI) agent" RSC Adv. (2015) 42762-42767 [IF=3.289]
     

  16. Jih Ru Hwu*, Mohit Kapoor, Shwu-Chen Tsay*, Chun-Cheng Lin, Kuo Chu Hwang, Jia-Cherng Horng, I-Chia Chen, Fa-Kuen Shieh, Pieter Leyssen, Johan Neyts*. "Benzouracil–coumarin–arene conjugates as inhibiting agents for chikungunya virus" Antiviral Research (2015) 103-109 [IF=4.909]
     

  17. Yu-Te Liao, Saikat Dutta, Ching-Hsuan Chien, Chien-Chieh Hu, Fa-Kuen Shieh, Chia-Her Lin*, Kevin C.-W. Wu*. "Synthesis of Mixed-Ligand Zeolitic Imidazolate Framework (ZIF-8-90) for CO2 Adsorption" Journal of Inorganic and Organometallic Polymers and Materials (2015) 251-258 [IF=1.308]
     

  18. Shanlin Qiao, Wei Huang, Zhengkun Du, Xianghui Chen, Fa-Kuen Shieh, and Renqiang Yang*. "Phosphine oxide-based conjugated microporous polymers with excellent CO2 capture properties" New Journal of Chemistry (2015) 136-141 [IF=3.277]
     

  19. Wei-Shang Lo, Szu-Mam Liu, Shao-Chun Wang, Hsiu-Pen Lin, Nianhan Ma*, Hsi-Ya Huang, and Fa-Kuen Shieh*. "A Green and Facile Approach to Obtain 100nm Zeolitic Imidazolate Framework-90 (ZIF-90) Particles via Leveraging Viscosity Effects" RSC Adv. (2014) 52883-52886 [IF=3.840]
     

  20. Hui-Hsu Gavin Tsai,* Jian-Bin Lee, Yuan-Ci Shih, Lei Wan, Fa-Kuen Shieh, and Chin-Yu Chen. "Location and Conformation of Amyloid β(25–35) Peptide and its Sequence-Shuffled Peptides within Membranes: Implications for Aggregation and Toxicity in PC12 Cells" ChemMedChem (2014) 1002-1011 [IF=2.968]
     

  21. Yu-Chain Sue, Jhe-Wei Wu, Shao-En Chung, Chao-Hsiang Kang, Kuo-Lun Tung, Kevin C.-W. Wu,* and Fa-Kuen Shieh*. "Synthesis of hierarchical micro-/mesoporous structures via solid-aqueous interface growth: zeolitic imidazolate framework-8 (ZIF-8) on siliceous mesocellular foams (MCF) for enhanced pervaporation of water/ethanol mixtures" ACS Appl. Mater. Interfaces (2014) 5192-5198 [IF=6.723]
     

  22. Ming-Hua Hsu,* Hong Chuang, Fong-Yu Cheng, Ying-Pei Huang, Chien-Chung Han, Kuan-Chuan Pao, Shih-Ching Chou, Fa-Kuen Shieh, Fu-Yuan Tsai, Chung-Chang Lin, Dian-Syue Wu and Chia-Ching Chang. "Simple and highly efficient direct thiolation of the surface of carbon nanotubes" RSC Adv. (2014) 14777-14780 [IF=3.840]
     

  23. Lin-Chiang Sherlock Huang, Kou-Hung Wu, Pi-Wen Ko, Cheng-Ying Hsieh, Kuan-Chuan Pao, Shih-Ching Chou, Fa-Kuen Shieh, Radhakrishnan Sureshbabu, Ming-Hua Hsu*. "Microwave assistance of labeling hippuric acid by I-131" Appl. Radiat. Isot. (2014) 53 – 57 [IF=1.231]
     

  24. Fa-Kuen Shieh,* Chia-Teng Hsiao, Yu-Chein Sue, Kuan-Wei Lin, Chang-Cheng Wu, Xi-Hong Chen, Lei Wan, Ming-Hua Hsu, Jih Ru Hwu, Hsien-Ming Kao, Chia-Kuang Tsung, and Kevin C.-W. Wu. "Size-Adjustable Annular Ring-Functionalized Mesoporous Silica as Effective and Selective Adsorbents for Heavy Metal Ions" RSC Adv. (2013) 25686 – 25689 [IF=3.708]
     

  25. Yung-Bin Kuo, Err-Cheng Chan, Jinn-Shiun Chen, Fa-Kuen Shieh*. "Fecal miRNAS as Biomarkers for the Detection of Colorectal Cancer" J. Gastroint. Dig. Syst., S12 (2013) [IF=2.406]
     

  26. Fa-Kuen Shieh,* Shao-Chun Wang, Sin-Yen Leo and Kevin C.-W. Wu*. “Water-Based Synthesis of Zeolitic Imidazolate Framework-90 (ZIF-90) with a Controllable Particle Size” Chem. Eur. J. 34 (2013) 11139 – 11142 Selected as Back Cover. [IF=5.696]
     

  27. Wei-Chieh Chang, Juti Rani Deka, Hao-Yiang Wu, Fa-Kuen Shieh,* Su-Yin Hwang,a Hsien-Ming Kao*. "Synthesis and characterization of large pore cubic mesoporous silicas functionalized with high contents of carboxylic acid groups and their use as adsorbents" Appl. Catal., B, (2013) 817 – 827 [IF=6.007]
     

  28. Hao-Yiang Wu, Fa-Kuen Shieh, Hsien-Ming Kao,* Yi-Wen Chen, Juti Rani Deka, and Kevin C. -W. Wu*. "Synthesis, Bifunctionalization and Remarkable Adsorption Performance of Benzene-Bridged Periodic Mesoporous Organosilicas Functionalized with High Loadings of Carboxylic Acid" Chem. Eur. J. (2013) 6358 – 6367 [IF=5.696]
     

  29. Shwu-Chen Tsay , Jih Ru Hwu, Raghunath Singha, Wen-Chieh Huang, Yung Hsiung Chan, Ming-Hua Hsu, Fa-Kuen Shieh, Chun-Cheng Lin, Kuo Chu Hwang, Jia-Cherng Horng, Erik De Clercq, Inge Vliegen, Johan Neyts* Rong-Jie Chein and Chia-Kuang Tsung. "Coumarins hinged directly on benzimidazoles and their ribofuranosides to inhibit hepatitis C virus” Eur. J. Med. Chem, (2013) 290-298 [IF=3.432]
     

  30. Fa-Kuen Shieh,* Chia-Teng Hsiao, Jhe-Wei Wu, Ya-Ling Bao, Yi-Hsin Liu, Lei Wan, Ming-Hua Hsu, Juti Rani Deka, Chia-Kuang Tsung, Hsien-Ming Kao*. "A bioconjugated design for amino acid-modified mesoporous silicas as effective adsorbents for toxic chemicals" J. Hazard. Mater. (2013) 1083 – 1091 [IF=4.331]
     

  31. Hsu YA, Lin HJ, Sheu JJ, Shieh FK, Chen SY, Lai CH, Tsai FJ, Wan L, Chen BH. "A Novel Interaction Between Interferon-Inducible Protein p56 and Ribosomal Protein L15 in Gastric Cancer Cells.", DNA Cell Biol. (2011) Sep;30(9):671-9. Epub 2011 May 25. [IF=2.072]
     

  32. Januszyk K, Fleissner MR, Atchabahian L, Shieh FK, Altenbach C, Martin SL, Guo F, Hubbell WL, Clubb RT. "Site-directed spin labeling electron paramagnetic resonance study of the ORF1 protein from a mouse L1 retrotransposon." Protein Sci. (2011) Jul;20(7):1231-43. doi: 10.1002/pro.651. Epub 2011 Jun 14. [IF=2.798]
     

  33. Hsu CM, Hsu YA, Tsai Y, Shieh FK, Huang SH, Wan L, Tsai FJ. "Emodin inhibits the growth of hepatoma cells: finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells." Biochem Biophys Res Commun. (2010) Feb 19;392(4):473-8. Epub 2009 Nov 4. [IF=2.595]
     

  34. Shieh, F.-K. and Reich, N. O. "AdoMet-dependent methyl-transfer: Glu119 is essential for DNA C5-Cytosine methyltransferase M.HhaI", J. Mol. Biol. (2007), 373, 1157. [IF=4.472]
     

  35. Youngblood, B. Y.; Shieh, F.-K.; Buller, F.; Bullock, T. and Reich, N. O. "S-Adenosyl-L-methionine-Dependent MethylTransfer: Observable Precatalytic Intermediates during DNA Cytosine Methylation", Biochemistry (2007), 46, 8766. [IF=3.368]
     

  36. Shieh, F.-K.; Youngblood, B. and Reich, N. O. "The Role of Arg165 Towards Base Flipping, Base Stabilization and Catalysis in M.HhaI", J. Mol. Biol. (2006), 362, 516-27. [IF=4.890]
     

  37. Youngblood, B.; Shieh, F.-K.; Rios, S. D. L.; Perona, J.-J. and Reich, N. O. "Engineered Extrahelical Base Destabilization Enhances Sequence Discrimination of DNA Methyltransferase M.HhaI", J. Mol. Biol. (2006), 362, 334-46. [IF=4.890]
     

  38. Chang, C.-A.; Shieh, F.-K.; Liu, Y.-L.; Chen, Y.-H.; Chen, H.-Y. and Chen, C.-Y. "Capillary Electrophoresis, Potentiometric and Luminescence Studies of Lanthanide (III) Complexes of 1,7-Dicarboxymethyl- 4,7,10-tetraazacyclododecane (DO2A)", J. C. S. Dalton Trans. (1998), 3243-3248. [IF=2.507]
     

  39. Chang, C.-A.; Shieh, F.-K.; Lu, Y.-L. and Chung, C.-S. "Effects of Chain Length and Terminal N-alkylation on the Protonation Constants Stability Constants of Some Transition Metal Complexes of Linear Tetraaza and Pentaaza Ligands", J. Chin. Chem. Soc. (Taipei) (1998), 45, 753-759. [IF=0.451]

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